Mesotherapy

Mesotherapy delivers small volumes of active compounds — vitamin and mineral blends, medications, peptide cocktails — through many shallow intradermal or subcutaneous injections distributed across the scalp. The premise is local delivery: placing agents at follicle depth rather than relying on topical penetration or systemic dosing.

The category’s defining feature is variability. Unlike PRP, which is always derived from the patient’s own blood, mesotherapy is defined by its technique rather than its contents: two clinics offering “mesotherapy” may inject entirely different cocktails on different schedules. Evidence follows the same pattern — some protocols and ingredients have supportive published data, others ride on habit — so the meaningful clinical questions are always what exactly is injected, at what dose, on what evidence.

In practice, scalp mesotherapy runs as a series of sessions using fine needles or injection devices, often positioned alongside first-line pharmacological treatment rather than instead of it, and sometimes combined with microneedling or PRP in layered protocols. Patient selection mirrors other non-surgical options: realistic candidates are early-to-moderate thinners with a confirmed diagnosis, not advanced baldness looking for an alternative to transplantation.

For clinics, mesotherapy carries two obligations. Regulatory: scalp injection is a medical act in most jurisdictions, with scope-of-practice rules on who may perform it. Editorial: a written protocol naming ingredients, concentrations, cadence and exclusion criteria. A service that cannot produce that document is not running a protocol — it is running a fashion.

Delivery follows a course logic: an induction series of sessions spaced weeks apart, then spaced maintenance if the patient responds — response being judged from standardised photographs and, ideally, trichoscopic comparison rather than mirror impressions. Documenting each session (cocktail, batch, volumes, sites, any reactions) is what turns a repeated injection into auditable clinical care, and it is the record a clinic will want if a regulator, or a patient, ever asks what exactly was given.